Tailored Intervention to Improve Medication Adherence in Patients With Hypertension

Pharmacist Intervention Programme in Secondary Care to Improve Medication Adherence in Patients With Hypertension

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01742923

Enrollment

532

Registered

2012-12-06

Start date

2012-12-31

Completion date

2014-09-30

Last updated

2015-11-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertension

Keywords

hypertension, medication adherence, motivational interviewing

Brief summary

Patients with hypertension have an increased risk of stroke and myocardial infarction. However, poor adherence to treatment with antihypertensives and lipid-lowering agents occurs frequently within this patient group. The purpose of this study is to investigate whether a complex tailored intervention in a hospital setting will lead to increased medication adherence and fewer cardiovascular events when compared to a usual care group. Interventions focus on motivational interviewing, medication review and telephone follow up.

Interventions

BEHAVIORALComplex tailored intervention

BEHAVIORALUsual care

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

Age: 18 years or older * Patients receiving ambulatory treatment for hypertension in a hospital setting * The patient or a carer usually dispenses the patient's medications * Patient lives in the Southern Region of Denmark * Written consent

Exclusion criteria

* Lives in a care home or institution * Receive dose dispensed medicine from a pharmacy * Medicine is dispensed by a nurse in the patient's home * Correctional mental health patients

Design outcomes

Primary

Measure	Time frame
Percent of patients that are at least 80% adherent (Medication possession rate > 0.8) to antihypertensives and statins	One year from inclusion

Secondary

Measure	Time frame
Non-persistence with antihypertensives and statins measured by percent of patients that are not supplied with medications for more than three continuous months	One year from inclusion
Reduction in systolic and diastolic blood pressure	One year from inclusion
Composite endpoint (stroke, myocardial infarction or cardiovascular death)	One year from inclusion

Countries

Denmark

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026