Single Blind Randomized Study to Determine the Sensitivity and Specificity of 2 Non-invasive Markers of Early Coronary Disease

Status

Terminated

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01742156

Enrollment

Registered

2012-12-05

Start date

2013-01-31

Completion date

2013-09-30

Last updated

2017-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary Artery Disease

Keywords

CAD, microangiopathy, patients, more likely, to have tortuosity, of conjunctival vessels

Brief summary

Diagonal ear lobe crease and microcirculatory disorder in the conjunctiva are both non invasive methods documented in the literature as early signs of coronary artery disease. We wish to study the sensitivity and specificity of both signs by conducting a single blind study involving patients with documented presence or absence of coronary artery disease via angiogram.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

20 Years to 70 Years

Healthy volunteers

Inclusion criteria

* age 20 to 70 years old * angiogram within past 12 weeks * stable during post angio period * willing to provide informed consent

Exclusion criteria

* previous eye surgery including cataract surgery * previous ophthalmologic disorders * previous surgeries involving ears or ear lobes

Design outcomes

Primary

Measure	Time frame
Presence of tortuosity of conjunctival vessels	1 year

Countries

Canada

Outcome results