Postoperative Atrial Fibrillation
Conditions
Brief summary
The primary aim of this study is to determine the safest and most effective therapeutic strategy to decrease the incidence of postoperative atrial fibrillation following cardiac surgery in an era with shorter ICU and hospital length of stay. A secondary goal is to evaluate the length of hospital stay associated with each treatment strategy.
Interventions
None listed
Sponsors
George Washington University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 100 Years
Healthy volunteers
Yes
Inclusion criteria
* age \> or = to 18 years * sinus rhythm * undergoing either coronary artery bypass graft surgery (CABG), valvular heart surgery or a combined procedure
Exclusion criteria
* received a class-I or class-III antiarrhythmic agent in the past six months * had second or third degree heart block * had a resting heart rate of less than 50 beats per minute * had a systolic blood pressure less than 100 mmHg * had severe asthma or severe chronic obstructive pulmonary disease * had uncontrolled heart failure * had a serum aspartate aminotransferase or alanine aminotransferase concentration greater than four times the upper limit of normal
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| occurrence of atrial fibrillation | postoperative day 0-day of discharge (an average of 5 days) | The primary endpoint of this study was also the occurrence of atrial fibrillation for any length of time requiring treatment as a result of symptoms or hemodynamic compromise. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| length of stay | participants will be followed for the duration of hospital stay, an expected average of 5 days | The secondary endpoint was the length of hospital stay after surgery. |
Countries
United States
Outcome results
None listed