Malnutrition
Conditions
Keywords
Nutritional supplement, Nutritional status, Physical functional activity, Nursing home elderly
Brief summary
To examine the effectiveness of a need-based nutritional intervention strategy in improving the nutritional and physical functional status of nursing home elderly.
Detailed description
Ninety-two nursing home residents aged 65 years or older and BMI \<25 were randomly assigned to the intervention or control groups. Subjects in the treatment group received a soy-protein-based nutritional supplement, if his/her BMI was \<24kg/m2 and nutritional score was \<24 according to the Mini Nutritional Assessment. The supplementation would be suspended if both conditions were not met. At baseline and every 4 weeks up to 24 weeks, thereafter, all subjects were measured for anthropometric parameters. At baseline, 12 weeks and 24 weeks subjects were measured for blood biochemical indicators, handgrip strength and Barthel's index.
Interventions
DIETARY_SUPPLEMENTNutritional supplement
Subjects will receive 50 g/day of a soy protein-based nutritional supplement containing 9.5 g protein, 250 kcal energy and all essential micronutrients
OTHERTreatment as usual
routine care
Sponsors
Asia University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Caregiver, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
65 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1. ≥ 65 years of age 2. BMI ≤ 25 (kg/m2) 3. ≥1 month of residency 4. Able to self-feed or receive oral-feeding 5. Non-bed-ridden 6. Cognitively able to answer the questionnaire
Exclusion criteria
1.Hospitalized or having acute infection/diseases
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Assessment of nutritional status with the Mini nutritional Assessment (MNA) | Baseline and every 4 weeks, up to 24 weeks | Change from baseline in MNA score at 4, 8, 12, 16, 20 and 24 weeks |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Biochemical indicators | Baseline, 12, and 24 weeks | Change from baseline in serum albumin and cholesterol concentrations, and hemoglobin, hematocrit and lymphocyte count status at 12, and 24 weeks. |
Other
| Measure | Time frame | Description |
|---|---|---|
| Physical functional status | Baseline, 12 and 24 weeks | Change from baseline in Barthel's index and handgrip strength at 12 and 24 weeks |
| Hospital admissions | Baseline, and 24 weeks | Frequency of outpatient visits, emergency visits and hospital admission (length of stay) during the study |
Countries
Taiwan
Outcome results
None listed