The Genetics Behind Vitamin D Status (VitDgen)

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01741233

Acronym

VitDgen

Enrollment

102

Registered

2012-12-04

Start date

2012-11-30

Completion date

2013-03-31

Last updated

2013-08-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vitamin D Deficiency

Keywords

SNPs, vitamin D, Vitamin D status, UVB irradiation, genetics

Brief summary

The overall purpose of the study is to investigate whether there is a relationship between 26 different single nucleotide polymorphisms (SNPs) in the vitamin D pathway, ultraviolet B (UV-B) irradiation of the skin and vitamin D status. The hypothesis is that vitamin D status are influated by different genetic genotypes in the vitamin D pathway.

Detailed description

In this study approximately 80 participants (over 18 years) are included. All the participants has previously participated in the VitmaD intervention study (NCT01184716) . Participants will in total receive 4 times UV-B irradiation (3 SED) with two day apart each time, to stimulate vitamin D production in the skin. The participants skintype will be measured. The study starts in January 2013 and runs to the end of Marts 2013. During this winter period, it is in Denmark not possible to produce vitamin D in the skin through sunlight exposure.

Interventions

GENETICVitDgen

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

BASIC_SCIENCE

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 60 Years

Healthy volunteers

Yes

Inclusion criteria

* Health participants over 18 years, that previously participated in VitmaD intervention study

Exclusion criteria

* skindiseases * intake of medicin that causes photosensitive skin * pregnant or nursing * sun vacation 3 month before the intervention * intake of vitamin D supplement 3 month before the intervention

Design outcomes

Primary

Measure	Time frame	Description
serum 25-hydroxyvitamin D	10 days	Measures the vitamin D status i serum at baseline and at the end of the project

Secondary

Measure	Time frame	Description
Skintest	10 days	Optimize scientific; measures pigmentation and redness of the skin. Are measured at baseline and at end of project

Countries

Denmark

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026