The Effect of tDCS on Motor Performance and Cortical Excitability

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01740843

Enrollment

Registered

2012-12-04

Start date

2012-08-31

Completion date

2013-06-30

Last updated

2014-02-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cortical Excitability, Motor Performance, tDCS

Brief summary

In this study the effect of tDCS intensity on motor performance and corticospinal (CS) excitability is evaluated. The investigators expect that a positive relationship between current intensity and motor performance/CS excitability.

Interventions

DEVICEtranscranial direct current stimulation (tDCS) (NeuroConn DC-stimulator)

The anode is fixed on the primary cortex and the cathode will be fixed on the contralateral supraorbital region.

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender

ALL

Age

18 Years to 85 Years

Healthy volunteers

Yes

Inclusion criteria

\- Healthy subjects

Exclusion criteria

* Contraindications for tDCS/TMS * TMS measurements have to be possible

Design outcomes

Primary

Measure	Time frame	Description
Change in motor performance	Baseline and POST (30 min after baseline) intervention	motor performance is assessed using different reaction time paradigms (simple reaction time, choice reaction time). This is done at baseline and immediately after the intervention (30 min after baseline)
Change in cortical excitability	Baseline and POST (30 min after baseline) intervention	Cortical excitability is measured using trancranial magnetic stimulation (TMS) measuring muscle evoked potentials (MEPs) at baseline and POST (30 min after baseline).

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026