The Effect of Anodal tDCS on Motor Learning in Multiple Sclerosis

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01740830

Enrollment

Registered

2012-12-04

Start date

2012-06-30

Completion date

2012-10-31

Last updated

2013-06-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anodal tDCS, Recruitment Curves

Brief summary

The current study investigates the effects of tDCS in patients with multiple sclerosis (MS). The investigators hypothesize that anodal tDCS will increase motor performance in patients with MS.

Interventions

DEVICETranscranial Direct Current Stimulation (tDCS) (Neuroconn DC-stimulator)

The anode will be fixed over the primary motor cortex. The cathode will be fixed over the contralateral supraorbital region.

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

TREATMENT

Masking

TRIPLE (Subject, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 70 Years

Healthy volunteers

Inclusion criteria

* at least 18 years old * male and female

Exclusion criteria

* relapse in the last 3 months * when not suitable for tDCS (screening) * if TMS measures can not be completed

Design outcomes

Primary

Measure	Time frame	Description
Motor performance on a unimanual sequence learning task	Baseline, during training and POST (30 min after baseline) intervention	Patients were instructed to perform a unimanual sequence-learning task consisting of sequential finger presses. The following parameters were measured: Correct sequences/mean inter tap interval (ITI), percentage correct key presses/mean ITI, percentage correct sequences, percentage correct key presses, mean ITI, and mean correct sequences in the performance interval.

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026