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Computerised Assessment of Visual Neglect Symptoms in Peripersonal Space

Computerised Assessment of Visual Neglect Symptoms in Peripersonal Space

Status
Terminated
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01740544
Acronym
KMS-Neglect 2
Enrollment
16
Registered
2012-12-04
Start date
2012-10-31
Completion date
2012-12-31
Last updated
2018-11-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Visual Neglect

Brief summary

Healthy subjects will undergo cathodal stimulation of the right posterior parietal Cortex (PPC) and assessment of neglect-like symptoms in the encircling monitor system (EMS) as well as in a standard clinical test (Test Battery for Attention Performance, TAP, Zimmermann & Fimm, 1993). The aim of this study is to investigate whether cathodal stimulation leads to poorer test performance.

Interventions

Cathodal tDCS applied over the right PPC

OTHERSham tDCS

Sham tDCS applied over the right PPC

Sponsors

Median Klinik Berlin-Kladow
CollaboratorUNKNOWN
NeuroCure Clinical Research Center, Charite, Berlin
CollaboratorOTHER
Center for Stroke Research Berlin
CollaboratorOTHER
Free University of Berlin
CollaboratorOTHER
Humboldt-Universität zu Berlin
CollaboratorOTHER
Charite University, Berlin, Germany
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
DIAGNOSTIC
Masking
DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender
ALL
Age
18 Years to 85 Years
Healthy volunteers
Yes

Inclusion criteria

* Younger subjects * aged between 18 and 35 years * ability to provide written informed consent * right-handedness * Elderly subjects * aged between 50 and 85 years * ability to provide written informed consent * right-handedness

Exclusion criteria

\-

Design outcomes

Primary

MeasureTime frameDescription
Test performance of young study participants in the encircling monitor system with/without cathodal stimulationComparison of the young subjects' performance with vs. without transcranial direct current stimulation (tDCS) in the following computerised tests: Star Cancellation (number of omissions, latency & crossing index; based on Rabufetti, 2012), Landmark (reaction times, accuracy; based on Giglia et al., 2011), Visual Detection (reaction times, omissions; based on Sparing et al., 2009), Extinction (number of correct responses; based on Niedeggen & Hoffmann, 2011)

Secondary

MeasureTime frameDescription
Test performance of elderly study participants in the encircling monitor system with/without cathodal stimulationComparison of the performance with vs. without transcranial direct current stimulation (tDCS) in the following tests: Star Cancellation, Landmark, Visual Detection, Extinction (see above)
Test performance of study participants in the Test Battery for Attention Performance (TAP) with/without cathodal stimulationComparison of reaction times and number of omissions in the left and right visual field in the TAP subtest Neglect with vs. without tDCS.
Comparison of visual search patterns between neglect patients and healthy subjects with cathodal stimulationComparison of visual search direction, structuredness (crossing index), and omissions in the Star Cancellation Test

Countries

Germany

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026