Perianal Abscess
Conditions
Brief summary
The aim of this study is to compare the effect of packing and non-packing on the healing rate of perianal abscess cavities. Secondary objectives are to assess quality of life, cost effectiveness and rate of abscess recurrence and fistula-in-ano formation. If there is no difference in time to healing and non-packing is shown to be safe, acceptable to the patient and cost effective, this approach may become more widely accepted.
Interventions
OTHERPacking of abscess cavity
OTHERExternal dressing
Application of external dressing whilst abscess cavity heals
Sponsors
North Western Research Collaborative
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Clinical diagnosis of acute primary perianal abscess * Have undergone surgical incision and drainage as an emergency
Exclusion criteria
* The abscess is the sequelae of concurrent disease or trauma * Fourniers gangrene is suspected * Unable to give informed consent
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Time to wound healing in days, defined as complete epithelialisation of the abscess cavity. | 1 day to 6 weeks | time to healing will be assessed in days |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Quality of life scores as determined by the Euro QoL EQ-5D-3L | 10 to 14 days | Quality of life scores as determined by the Euro QoL EQ-5D-3L will be measured at 10-14 days following incision and drainage of abscess |
Other
| Measure | Time frame |
|---|---|
| Abscess recurrence rate | 0 days to 12 months |
| Fistula-in-ano formation rate | 0 days to 18 months |
| Cost | 0 days to 18 months |
Outcome results
None listed