Cholangiocarcinoma
Conditions
Keywords
Cholangiocarcinoma, Pathologic, Digestive System, Neoplasms, Neoplasms by Site, Digestive System Diseases, Bile Duct Diseases, Biliary Tract Diseases, Pathological Conditions, Constriction, Adenocarcinoma, Carcinoma
Brief summary
The purpose of this study is to compare endoscopic radiofrequency ablation with photodynamic therapy for inoperable cholangiocarcinoma
Interventions
PROCEDURESelf expanding metallic stent (SEMS)
Self expanding metallic stent
PROCEDUREEndoscopic radiofrequency ablation (ERFA)
Endoscopic radiofrequency ablation
PROCEDUREPhotodynamic therapy (PDT)
Photodynamic therapy
Sponsors
Guangzhou Medical University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* Age ≥ 18 years old * Pathologically or radiologically confirmed biliary malignant * Inoperability by staging
Exclusion criteria
* Cholangiocarcinoma with widespread metastasis * Coagulopathy (INR \> 2.0 or prothrombin time \> 100 sec or platelet count \< 50,000) * Prior SEMS placement * Pregnancy * Eastern Cooperative Oncology Group (ECOG) performance status ≥ 3 ) * Life expectancy \< 3months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| stent patency | 6 months |
Secondary
| Measure | Time frame |
|---|---|
| overall survival rate | 3 years |
Countries
China
Contacts
Primary ContactHuihong Liang, MD
Outcome results
None listed