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Dexamethasone Added to Levobupivacaine Improves Postoperative Analgesia

Dexamethasone Added to Levobupivacaine Improves Postoperative Analgesia After Supraclavicular Brachial Plexus Blockade

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01739270
Enrollment
55
Registered
2012-12-03
Start date
2012-10-31
Completion date
Unknown
Last updated
2015-07-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Analgesia, Brachial Plexus Anesthesia

Keywords

analgesia, regional anesthesia, surgery, duration of analgesia, dexamethasone added to levobupivacaine compared to levobupivacaine alone

Brief summary

Adding dexamethasone to local anesthetic will significantly prolong duration of brachial plexus anesthesia and analgesia.

Detailed description

Operations of upper extremities are often performed in regional anesthesia blocks. Single-injection blocks are effective, but time limited. Adding 4mg of dexamethasone to 0.5% levobupivacaine will significantly prolong duration of brachial plexus anesthesia and analgesia for fracture operations of upper extremity. This effect will result in less opioid use postoperatively.

Interventions

PROCEDUREsupraclavicular brachial plexus block

Sponsors

University Hospital Dubrava
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Investigator)

Eligibility

Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No

Inclusion criteria

* patients aged 18 years or older * ASA (American Society of Anesthesiologists) physical status I, II or III

Exclusion criteria

* refusal of the patients to give informed consent * preexisting coagulation disorders * local infection at the site of the block * neuropathy * drug or alcohol abusers * known allergy to the drug used in study * operation time exceeding six hours

Design outcomes

Primary

MeasureTime frameDescription
duration of analgesia24 hour postoperativelyDuration of analgesia after supraclavicular block

Secondary

MeasureTime frame
postoperative analgesic consumption24 hour

Countries

Croatia

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026