Growth Response in Girls With Turner Syndrome

Growth Response in Girls With Turner Syndrome During a Three-year GH Treatment Comparing Two Dose Regimens. Identification of Predictive Factors of Growth Response

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01734486

Enrollment

Registered

2012-11-27

Start date

1996-09-23

Completion date

2003-05-21

Last updated

2017-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Genetic Disorder, Turner Syndrome

Brief summary

This trial is conducted in Europe. The aim of the trial is to evaluate growth response of two somatropin dose regimens in girls with Turner Syndrome.

Interventions

DRUGsomatropin

0.9 UI/kg/week. Subcutaneous injection for 3 years

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

FEMALE

Healthy volunteers

Inclusion criteria

* Turner syndrome * If age below 3 years, either body height below - 1 SD (standard deviation) with average growth velocity according to chronological age or body height below 0 SD with growth velocity below -1 SD according to chronological age * If age above 3 years, body height below - 1 SD with average growth velocity according to chronological age * Measured parental height available * Written informed consent

Design outcomes

Primary

Measure	Time frame
Height gain, SDS (Standard Deviation Score)	—
Height gain in cm	—

Secondary

Measure	Time frame
Height	—
Bone maturation	—

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026