Major Depressive Disorder
Conditions
Keywords
Family psychoeducation, Major depressive disorder, Family burden
Brief summary
The purpose of this study is to examine the effectiveness of brief multifamily psychoeducation to relieve the psychological distress of families of patients with chronic major depression and to improve their family functioning.
Detailed description
Major depressive disorder (MDD) is a long-lasting illness with significant effects on the patient's family, social life, and work life. Treatment failure results in a low recovery rate and frequent relapses. Relatives of patients with MDD are fraught with heavy psychosocial burden and show increased rates of depression and anxiety. Among relatives of patients with MDD, the patient's behavior and mood disturbance and relative's emotional distress were associated with the relatives' burden. Family psychoeducation is recognized as part of the optimal treatment for patients with psychotic disorder. This intervention has been shown to reduce the rates of relapse and hospitalization among individuals with psychotic disorders and is recognized as an evidenced-based treatment for psychotic disorder. Several randomized controlled trials have found that family psychoeducation is effective in enhancing the course of bipolar disorder. However, there are few studies on psychoeducation of families of patients with MDD. The purpose of this study is to examine the effectiveness of brief multifamily psychoeducation to relieve the psychological distress of families of patients with chronic major depression and to improve their family functioning, in a randomized controlled trial.
Interventions
BEHAVIORALFamily psychoeducation
Family psychoeducational therapy every two weeks for six weeks in addition to treatment as usual administered by physicians
Sponsors
Nagoya City University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 85 Years
Healthy volunteers
No
Inclusion criteria
1. Meets the criteria for Major Depressive Disorder (MDD) according to DSM-IV. 2. Receives antidepressant therapy. 3. The patient had the first episode of MDD more than one year ago. 4. Currently fulfills the diagnostic threshold for major depressive episode or partial remission. 5. The patient and their family member(s) are aged between 18 and 85 years. 6. The patient has lived with his/her family at the time of participating in this study and is expected to live with his/her family during the investigation period.
Exclusion criteria
1. Patients who undergo electroconvulsive therapy (ECT) during the investigation period. 2. Patients who are at serious suicidal risk.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The change of total score of K6 of family members | The base line, 8, 16 and 32 | The K6 questionnaire is a six-item self-report questionnaire that was developed to screen for DSM-IV depressive and anxiety disorder. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| The change of total score of Family Attitude Scale(FAS) of family members | The base line, 8, 16 and 32 | The Family Attitude Scale(FAS) is a 30-item self report inventory and measures families' Expressed Emotion(EE). |
Countries
Japan
Outcome results
None listed