Obesity
Conditions
Brief summary
The investigators performed a 12-week, randomized, double-blind, placebo-controlled human trial to evaluate the efficacy and safety of Fermented Cinnamon Vine Powde on decrement of body fat. The investigators measured decrement of body fat parameters , including abdominal fat, Body Fat Mass, LDL-C, HDL-C, Total Cholesterol and triglyceride, and monitored their blood pressure.
Interventions
DIETARY_SUPPLEMENTFermented Cinnamon Vine Powder
Fermented Cinnamon Vine Powder (30g/day)
DIETARY_SUPPLEMENTPlacebo
Placebo (30g/day)
Sponsors
Chonbuk National University Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
19 Years to 55 Years
Healthy volunteers
Yes
Inclusion criteria
* Males and females 19-55 years old * BMI(body mass index) ≥ 25 kg/m\^2 or WC(Waist Circumference) ≥ 90(men), WC ≥ 85(women) * Able to give informed consent
Exclusion criteria
* Significant variation in weight(more 10%) in the past 3 months * Allergic or hypersensitive to any of the ingredients in the test products * History of reaction to any of the test products or of gastrointestinal diseases such as Crohn's disease or gastrointestinal surgery * History of alcohol or substance abuse * Participation in any other clinical trials within past 2 months * Laboratory test, medical or psychological conditions deemed by the investigators to interfere with successful participation in the study * Pregnant or lactating women etc.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Changes in abdominal Fat | 12 weeks | Abdominal Fat was measured in study visit 1(0 week) and visit 3(12 week). |
| Changes in Body Fat Mass | 12 weeks | Body Fat Mass was measured in study visit 1(0 week) and visit 3(12 week). |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Changes in LDL-cholesterol(Low Density Lipoprotein - Cholesterol) | 12 weeks | LDL-C(Low Density Lipoprotein - cholesterol) was measured in study visit 1(0 week) and visit 3(12 week). |
| Changes in HDL-Cholesterol(High Density Lipoprotein - Cholesterol) | 12 weeks | HDL-cholesterol(High Density Lipoprotein - cholesterol) was measured in study visit 1(0 week) and visit 3(12 week). |
| Changes in total cholesterol | 12 weeks | Total cholesterol was measured in study visit 1(0 week) and visit 3(12 week). |
| Changes in Triglycerides | 12 weeks | Triglyceride was measured in study visit 1(0 week) and visit 3(12 week). |
Countries
South Korea
Outcome results
None listed