Dementia
Conditions
Keywords
rehabilitation, exercise, fall, muscle, vibration, mobility, cognition
Brief summary
The whole body vibration exercise group will have significantly more improvement in mobility, muscle strength, balance, balance confidence, and cognitive function with a lower fall rate than the control group.
Interventions
The whole body vibration will be delivered by a platform that can generate vibration signals (Powerplate). The total duration of vibration exposure per session will range from 4 to 6 minutes. The vibration bouts (30-45 seconds per bout) will be interspersed with a 1 to 2 minutes of rest period. While standing on the vibration platform, subjects will be instructed to repeat two exercises: (1) static semi-squats, and (2) dynamic semi-squats.
BEHAVIORALConventional exercise
The conventional exercise training will involve a combination of upper limb and lower limb stretching and strengthening exercises, balance training, and gait re-education.
Sponsors
Chinese University of Hong Kong
The Hong Kong Polytechnic University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
65 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* a diagnosis of mild or moderate dementia, with a Clinical Dementia Rating (CDR) of 1 to 2, and a Cantonese Mini-mental State Examination (CMMSE) score at 10 or above but below the local cutoff for dementia (18-22, depending on education level) * able to stand for at least 1 minute with or without hand support * living in the community * having an informed consent (from the primary caregiver)
Exclusion criteria
* significant musculoskeletal conditions (e.g. amputations) * metal implants in the lower extremity * recent fracture in the lower extremity * vestibular disorders * peripheral vascular disease * other serious illnesses or contraindications to exercise.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Timed-up-and-go test | week 0 | A measure of functional mobility |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Quality of Life in Alzheimer's disease | week 0 | — |
| Berg balance scale | week 0 | — |
| Mini-Mental State Examination | week 0 | — |
| Activities-specific balance confidence scale | week 0 | — |
| five times sit-to-stand test | week 0 | — |
| incidence of falls | daily starting from week 0 to week 33 | Incidence of falls will be recorded by using fall diaries. |
Countries
Hong Kong
Contacts
Primary ContactMarco Pang, PhD
Outcome results
None listed