The Learning and Memory of the Experience of Pain

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01731314

Enrollment

Registered

2012-11-21

Start date

2013-01-31

Completion date

2018-01-31

Last updated

2019-08-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain

Brief summary

This study investigates the learning and memory of pain.

Interventions

BEHAVIORALLearning and Memory of Pain

Study design

Allocation

RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

OTHER

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Yes

Inclusion criteria

1. Male and female healthy volunteers. 2. 18-65 years of age. 3. Right-handed. 4. Fluency in English. Ability to read and understand English; English can be a second language provided that the participant feels that he/she is able to understand all the questions used in the assessment measures.

Exclusion criteria

1. Any previous experience with conditioned analgesia/hyperalgesia paradigms. 2. Presence of any illness or medication use that is judged to interfere with the trial. For example: psychiatric disorder according to the DSM-IV manual, medication that can influence cognition or emotional processing, i.e. sleep medication, antidepressants, anti-convulsants or opioids. 3. Unwillingness to receive brief pain stimulation administered by a heat probe on the hand. 4. Instability of responses to experimental heat pain 5. Any contraindications to fMRI scanning for subjects in Experiment 2 (including metal implants, claustrophobia, history of head trauma, and pregnancy). 6. Peripheral neuropathy.

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026