Weight Management
Conditions
Keywords
obesity, isolated soy protein, satiety, food intake
Brief summary
Proteins are known to be more satiating than the other macronutrients; however, the type and amount of protein needed to induce a significant effect on satiety (fullness between meals) is sometimes difficult to determine. In this study, 2 differentially processed isolated soy proteins will be tested for satiety using subjective visual analogue scales. The amount of food consumed following intake of the isolated soy proteins will be measured 3 hours after consuming the proteins. The hypothesis is that differentially processed isolated soy proteins will show unique satiety responses.
Interventions
DIETARY_SUPPLEMENTDry-Blended Beverage
Sponsors
DuPont Nutrition and Health
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
* BMI between 20 and 30 kg/m2 * Age between 18-65y * Unrestrained eater (score\<12) * Regularly consume 3 meals per day * Moderate exercise (eg running, aerobics classes, other sports activities) of no more than 7 hours per week
Exclusion criteria
* use of drugs that influence carbohydrate or lipid metabolism (eg. hypoglycemic agents, antibiotics taken less than 6 weeks before study entry, glucocorticoids, anti-diarrheal medication, weight loss medication, and anti-diabetic medication) * presence of any significant disease (eg gastrointestinal diseases, diabetes, a CVD event less than 12 weeks from study entry, current hepatic disease, etc) * use of special dietary treatments within 4 weeks of study (eg weight loss diet, extremely high or low carbohydrate/protein/fat diet, use of meal replacements more than once a day) * use of supplements within 1 week of study (does not include vitamin supplements or supplements which are routinely taken and were initiated 4 weeks before the study and which will be continued during the study period) * restrained eater (score\>12) * weight change (absolute body weight change of ≥ 10%) within the previous 6 weeks * alcohol intake \>2 drinks/day * food allergies of any kind * swallowing difficulties * exercising more than 7 hours per week
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Subjective Satiety | 3 hours | Measure subjective satiety using visual analogue scales |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Ad Libitum Food Intake | 30 minutes | At the end of 3 hours after consuming test diets, measure the amount of food consumed for 30 mins |
Countries
Canada
Outcome results
None listed