The Significance of Vitamin D Storage in Adipose Tissue

Status

Withdrawn

Phases

Phase 2

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01728987

Enrollment

Registered

2012-11-20

Start date

2016-08-31

Completion date

2019-02-28

Last updated

2016-11-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity

Brief summary

The study will examine the role of adipose tissue in vitamin D physiology, particularly its role as a depot. the study is randomized double blind and placebo controlled.

Detailed description

vitamin d versus placebo will be given for 12 months. Biopsies will be taken at baseline and every 6 month for 2 years. Blood samples will be collected every 6th month. the study will thus give information on storage during vitamin d supplementation as well as use of vitamin d fat stores after stopping vitamin D supplementation

Interventions

DRUGcholecalciferol

as in arm description

DRUGplacebo

capsule looking identical to the cholecalciferol capsule

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

BASIC_SCIENCE

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

20 Years to 75 Years

Healthy volunteers

Yes

Inclusion criteria

* healthy subjects

Exclusion criteria

* hypercalcemia * pregnancy * women without safe contraception

Design outcomes

Primary

Measure	Time frame
vitamin D in adipose tissue biopsies	12 months

Secondary

Measure	Time frame
rate of decline of 25ohd in serum	12 months

Countries

Norway

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026