Ribose and Sport Performance

The Effect of Ribose on Performance and Recovery in Athletes

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01727479

Enrollment

Registered

2012-11-16

Start date

2012-08-31

Completion date

2013-01-31

Last updated

2016-12-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sports

Keywords

Peak VO2 consumption, 3km time trial, fatigue perception, lactate, time to complete

Brief summary

Investigate the acute effect of ribose supplementation on performance and recovery in athletes.

Interventions

OTHERRibose

After each of the 3km time trial (3 in total), participants will be asked to drink the experimental product (or placebo) incorporated in a sports drink.

OTHERPlacebo

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

PREVENTION

Masking

TRIPLE (Subject, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 50 Years

Healthy volunteers

Yes

Inclusion criteria

* Men and women * Training volume \> 7hrs/week * VO2 max \> 40 and 45 mg/kg/min (for women and men respectively) * Otherwise healthy individuals

Exclusion criteria

* Pregnant or breastfeeding women * Individuals with endocrine disorders, hypercholesterolemia, cardiovascular diseases, gut diseases, cancer, anemia, hypoglycemia * Medication for lipids, diabetes, hypertension, inflammation, autoimmune diseases, mood disorders * Excessive alcohol consumption (more than two drinks by day for men, one for women), smoking, drug use, supplements or natural products consumption during the study

Design outcomes

Primary

Measure	Time frame
Change in time to complete the third of 3 consecutive 3km time trials on bike	baseline and 1 week

Secondary

Measure	Time frame	Description
Performance on the 3 consecutive 3km time trials on bike	baseline and 1 week	Performance measures: peak power (watts/kg), mean power (watts/kg), time to peak power (sec), total work (kJ) and maximum cadence (RPMmax)

Other

Measure	Time frame	Description
Fatigue perception after each of the 3 consecutive 3km time trials on bike	baseline and 1 week	Post-exercise fatigue perception on visual analog scale (VAS)
Peak Vo2 consumption during each of the 3km time trials on bike	baseline and 1 week	—

Countries

Canada

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026