Laparoscopy, Methylene Blue, Tubal Patency
Conditions
Brief summary
1. Methylene blue in laparoscopy use for tubal patency assessment 2. Methylene blue could have negative effect on sperm motility, oocyte granulosa cell and fertility. 3. tubal washing after Methylene blue administration could be effective in pregnancy rate after operation.
Detailed description
women with unexplained infertility and without any problem during laparoscopy and hysteroscopy entered in the study.After randomization in one group after dye test,washing with normal saline was done until all of visible Methylene blue removed.In second group washing with normal saline did not done. pregnancy rate until three months after operation was followed without any intervention.
Interventions
DRUGmethylen blue &normal saline
Washing after dye injection
DRUGmethylene blue
DRUGmetheylne blue with normal saline
Sponsors
Pourmatroud, Elham, M.D.
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
FEMALE
Age
20 Years to 38 Years
Healthy volunteers
Yes
Inclusion criteria
* women with unexplained infertility
Exclusion criteria
* any intervention during operation like ovarian drilling or septum resection
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pregnancy rate | up to 12 weeks |
Secondary
| Measure | Time frame |
|---|---|
| complications rate in two group | Up to 12 weeks |
Other
| Measure | Time frame |
|---|---|
| Abortion rate | Up to 12 weeks |
Countries
Iran
Outcome results
None listed