Post-operative Vomiting
Conditions
Keywords
post-operative vomiting
Brief summary
Second only to pain, nausea and vomiting are the most uncomfortable complications of surgery and anesthesia. Unfortunately, our best defense against post-operative nausea and vomiting, a medicine called ondansetron (Zofran), is in dire national shortage. Consequently, non-pharmacological methods of prevention and treatment for post-operative nausea and vomiting have increased import. Following emergence from general anesthesia, children often request food and drink. There have been no studies to date that definitively determine the optimal first food or drink choice for these children. This study proposes to randomize children to either water or juice first intake following surgery. The investigators expect to find that children who consume glucose are less likely to vomit than those who first receive water.
Interventions
OTHERApple Juice
OTHERWater
Sponsors
University of North Carolina, Chapel Hill
Study design
Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
PREVENTION
Masking
DOUBLE (Caregiver, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
2 Years to 18 Years
Healthy volunteers
Yes
Inclusion criteria
* Dental surgery * Tonsillectomy and adenoidectomy * Strabismus surgery * Age 2-18
Exclusion criteria
* Patient refusal * Parent refusal * Allergy / contraindication to ondansetron * Prone to vomiting * Inpatient * Preoperative anxiolysis with ketamine * Recovery location other than PACU * Nil per os at baseline * Presence of enteric tube * Contraindication to any part of the study protocol
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Post-operative Vomiting | 24 hr post-op | Patients will be assessed for vomiting upon entry to PACU until 24 hours post-operatively. |
Countries
United States
Outcome results
None listed