Angioplasty of Left Main - lAriboisiere Registry

Prospective Registry in Patients With Unprotected Left Main Disease Treated by Percutaneous Coronary Intervention: The ALMA (Angioplasty of Left Main - lAriboisiere) Registry

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01725373

Acronym

ALMA

Enrollment

125

Registered

2012-11-12

Start date

2007-01-31

Completion date

2013-11-30

Last updated

2014-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary Artery Disease

Keywords

left main, stent,angioplasty

Brief summary

In patients with unprotected left main disease (ULMD), angioplasty is emerging as an alternative technique. The investigators aimed to determine the rate of major cardiovascular events in patients treated by angioplasty for ULMD in a real world registry.

Detailed description

Current guidelines recommend coronary artery bypass graft surgery as the gold standard treatment in patients with unprotected left main disease. However, patients with ULMD and high surgical risk score or favourable anatomy are still referred for angioplasty. Recently, several studies and registries comparing surgery and percutaneous intervention with drug eluting stents report similar results regarding cardiovascular death and myocardial infarction in patients with multivessel coronary artery disease including unprotected left main disease. The aim of the study is to evaluate major cardiovascular events in a real world registry.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* stable or unstable angina and/or documented ischemia * 50% de novo ULMD referred for angioplasty

Exclusion criteria

* acute coronary syndrome with ST elevation, * cardiogenic shock or out of hospital cardiac arrest

Design outcomes

Primary

Measure	Time frame	Description
Major cardiovascular events (MACCE)	One year	Major cardiovascular events (MACCE)were measured after 1 year follow-up. MACCE included all-cause of death, stroke, myocardial infarction, and repeat revascularizations. Non-Q-wave myocardial infarction was defined using universal definition with troponin I. Stent thrombosis was defined according to the Academic Research Consortium definition as definite, probable, or possible and as early or late after the index procedure. Repeat revascularization was composed of any repeat percutaneous intervention or surgical bypass.

Countries

France

Outcome results