Anti-Mullerian Hormone Levels Before and After an Open Myomectomy

Anti-Mullerian Hormone Levels Variations Following an Open Myomectomy

Status

Terminated

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01723085

Enrollment

Registered

2012-11-07

Start date

2012-03-31

Completion date

2015-12-31

Last updated

2018-07-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anti-Mullerian Hormone

Keywords

Anti-Mullerian hormone, Myomectomy, Laparotomy

Brief summary

Anti-Mullerian hormone (AMH) is a marker for ovarian reserve. It is well known that ovarian surgery for endometriosis lowers Anti-Mullerian hormone, but little is known for other surgeries. We seek to investigate the hormone variations before and after an open myomectomy. Hypothesis: Anti-Mullerian hormone levels drop following surgery but return to normal levels in a few months

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 42 Years

Healthy volunteers

Inclusion criteria

* 18 to 42 years old * Requiring open myomectomy for any indication

Exclusion criteria

* Incapable of informed consent * Use of hormonal contraception or Gonadotropin-releasing hormone agonists in the past 3 months * Woman over 42 years old * Post-menopause women * Positive B-human chorionic gonadotropin the day of surgery * Ovarian surgery (at the same time) * Pre-operative AMH below 0.3 ng/mL

Design outcomes

Primary

Measure	Time frame	Description
Anti-Mullerian Hormone levels variation	6 months	Anti-Mullerian Hormone levels before and 6 months after surgery

Countries

Canada

Outcome results