Intra Operative Fluid Management
Conditions
Keywords
dopamine, laparoscopy, fluid management
Brief summary
Aim of this study was to investigate the cardiac and renal responses to the administration of different amount of crystalloids, with and without dopamine, during gynaecological laparoscopic surgery.
Interventions
DRUGDopamine
Sponsors
Catholic University of the Sacred Heart
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
FEMALE
Age
24 Years to 42 Years
Healthy volunteers
No
Inclusion criteria
* ASA I * age 24-42 * patients undergoing gynaecological laparoscopy
Exclusion criteria
* cardiovascular diseases * renal and endocrine disorders * obesity (BMI \> 30 Kg/m2) * the assumption of drugs that could interfere with renal parameters considered in the study
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| estimated glomerular filtration rate, tissue Doppler imaging, E/Ea | patients will be followed for the duration of surgery, an expected average of 3 hours | EGFr, tissue Doppler imaging and E/Ea are registered after the induction of pneumoperitoneum and Trendelemburg position, and compared to those registered before the induction of anesthesia. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| total intra operative diuresis (TID) | patients will be followed for the duration of surgery, an expected average of 3 hours | TID will be measured at the end of surgery |
Countries
Italy
Outcome results
None listed