General Anesthesia, Indwelling Urinary Catheter, Male Patients
Conditions
Keywords
Catheter Related Bladder Discomfort, Dorsal Penile Nerve Block
Brief summary
Catheter-related bladder discomfort (CRBD) secondary to an indwelling urinary catheter is defined as an urge to void or discomfort in the supra-pubic region. This symptom complex may cause patient agitated and exacerbated postoperative pain. In clinic, dorsal penile nerve block (DPNB) was applied for penile surgery including circumcision and some anterior urethra surgery. The investigators hypothesize that DPNB relive CRBD for male patients with indwelling urinary catheter under general anesthesia.
Detailed description
CRBD is not uncommon in the postoperative period, especially in male patients who have had urinary catheterization after anesthetic induction under general anesthesia, and this symptom complex may cause patient agitated and exacerbated postoperative pain. According to the previous study, i.v. tramadol 1.5 mg/kg administered 30 min before extubation results in reduction in the incidence and severity of CRBD. In clinical practice, tramadol is associated with side effects including nausea, vomiting, sedation, etc. Clinically, dorsal penile nerve block (DPNB) was applied in penile surgery, and got satisfactory pain relief effect postoperatively without side effects related to tramadol. Besides, we observed patients underwent urethra surgery with urinary catheter left in situ seldom complained of CRBD if DPNB and RB performed at the end of operation. We hypothesized that DPNB could relieve DPNB for male patient with indwelling urinary catheter insertion after induction of general anesthesia. In this study we compare the efficacy of dorsal penile nerve block (DPNB) with 0.33% ropivacaine and intravenous tramadol 1.5mg/kg in prevention of CRBD, as well as the incidences of side effects postoperatively.
Interventions
PROCEDUREDPNB
Patients receive DPNB 30min before extubation at the end of operation
DRUGTramadol
Patients receive intravenous tramadol 1.5mg/kg 30min before extubation at the end of operation.
Sponsors
West China Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
MALE
Age
18 Years to 50 Years
Healthy volunteers
No
Inclusion criteria
* Informed consent signed * Male adult patient, aged 18\ 50 years old, ASA I\ III * Surgery under general anesthesia
Exclusion criteria
* Bladder dysfunction, such as overactive bladder * A history of bladder outflow obstruction * Prostate disease, such as benign prostate hyperplasia, etc. * Disturbance of central nervous system
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence and severity of CRBD | up to 6 months |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Visual analogue scale (VAS) for postoperative pain | up to 6 months | — |
| Postoperative fentanyl requirement | up to 6 months | — |
| Side effects | up to 6 months | 1. the level of sedation. 2. postoperative nausea vomiting (PONV) 3. incidence of respiratory depression 4. incidence of agitation, and delirium |
Other
| Measure | Time frame |
|---|---|
| Acceptance of indwelling urinary catheter | up to 6 months |
Countries
China
Outcome results
None listed