Childhood Obesity
Conditions
Keywords
boys, obesity, glucose, sucrose, high-fructose corn syrup-55
Brief summary
The purpose is to determine the effect of sugars in solution on food intake and subjective appetite in 9- to 14-year-old normal weight boys. The investigators hypothesize that food intake after all sugars-containing solutions will be decreased in comparison to the control solution, with similar reductions in FI between high-fructose corn syrup -55 (HFCS-55) and sucrose. Food intake will be measured 60 minutes after consumption of 50g of HFCS-55, sucrose or glucose, or a control treatment. Subjective appetite will be measured at 15, 30, 45, 60 and 90 minutes.
Interventions
DIETARY_SUPPLEMENTwater with Sucralose
DIETARY_SUPPLEMENTwater with HFCS
DIETARY_SUPPLEMENTwater with glucose
DIETARY_SUPPLEMENTwater with sucrose
Sponsors
Mount Saint Vincent University
Toronto Metropolitan University
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
PREVENTION
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
MALE
Age
9 Years to 14 Years
Healthy volunteers
Yes
Inclusion criteria
* Healthy, boy, born at full term and normal birth weight
Exclusion criteria
* Girl, on restricted diet, taking medication that affect appetite or food intake, have significant learning, behavioral, or emotional difficulties
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Food intake (kcal) | measured at 60 minutes after the treatment |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Subjective appetite (mm) | 0-90 minutes | Subjective appetite (in mm) by visual analogue scale will be determined at 0, 15, 30, 45, 60 and 90 minutes. |
Countries
Canada
Outcome results
None listed