Study of Variables Related to the Discontinuation of Mechanical Ventilation in Patients With Head Injury

Evaluation of Integrated Predictive Index of Weaning From Mechanical Ventilation in Patients With Traumatic Brain Injury

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01713010

Acronym

INDEXTBI

Enrollment

Registered

2012-10-24

Start date

2012-03-31

Completion date

2012-12-31

Last updated

2012-10-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mechanical Ventilation Complication, Traumatic Brain Injury, Weaning Failure

Keywords

Keywords provided by Atlantic Health System:, Rapid Shallow Breathing Index, Mechanical Ventilation, Additional relevant MeSH terms:, Respiration Disorders, Traumatic Brain Injury, Weaning Failure, Mechanical ventilation complication

Brief summary

The purpose of this study is to evaluate physiological variables to the decision about the appropriate time to discontinuation of mechanical ventilation in patients with traumatic brain injury. It is expected that these variables are effective in predicting the outcome of weaning from mechanical ventilation.

Detailed description

The aim of this study is to evaluate the effectiveness of integrated pressure index of airway occlusion x index breathing fast and shallow (p 0.1 x f/VT) in predicting success and failure of weaning from mechanical ventilation in patients with traumatic brain injury.

Interventions

OTHERPredictive indexes of weaning from mechanical ventilation

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Traumatic Brain Injury (TBI) * Patients using artificial airway (intubation and / or tracheostomy) * Recovery from the acute phase of the disease underlying * Both sexes * Ventilation mode pressure support (PSV), pressure support (PS) required to ensure a tidal volume (VT) = 6 to 8 ml / kg * Age over 18 years * Hemoglobin \> 7 g/dL * Duration of mechanical ventilation longer than 24 hours * Body temperature \< 38 degrees * pH ≥ 7.30 * PaO2 ≥ 60 mmHg with FiO2 ≤ 0.4 and PEEP ≤ 8 cmH2O * Glasgow Coma Scale ≥ 8 or tracheostomized * Sedative agents minimum dosages to to maintain values of 2 or 3 on the Ramsay Scale

Exclusion criteria

* Admitted to the ICU with artificial airways held in other institutions * Surgery scheduled for the next 72 hours * Withdrawal of consent from parents at any stage of the research

Design outcomes

Primary

Measure	Time frame
Result weaning mechanical ventilation in patients with traumatic brain injury,analyzing success and failure of weaning by 0.1 p and f / VT.	8 months

Countries

Brazil

Contacts

Primary Contactcamila marques dias

camilamd15@yahoo.com.br55 34 33388655

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026