Orbital Atrophy
Conditions
Keywords
Anophthalmic orbits, autologous fat, platelet rich plasma, orbital atrophy, anophthalmos, cannula
Brief summary
After people lose an eye, for whatever reason, they often experience fat atrophy of the tissues in the orbit. This leads to a sunken appearance that is often not correctable by a cosmetic shell prosthesis. Current techniques to correct this deformity are inadequate/ invasive. Injection of various gels (Restylane, Radiesse) are temporary had have their own disadvantages. This study seeks to demonstrate an improvement in the retention of injected autologous fat by mixing in autologous PRP (platelet rich plasma).
Interventions
PROCEDUREautologous fat grafting with PRP to anophthalmic orbits
Sponsors
Fox, Donald Munro, M.D., P.C.
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
21 Years to 70 Years
Healthy volunteers
Yes
Inclusion criteria
anophthalmos, orbital atrophy -
Exclusion criteria
poor anesthesia risk, people outside a 100 mile radius of New York City \-
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Improved retention of autologous fat injected into anophthalmic sockets | 1-5 yrs | Non contrast MRIs of the orbits are obtained before, immediately after, and one year after injection of autologous fat mixed with autologous PRP (platelet rich plasma) |
Countries
United States
Outcome results
None listed