Glaucoma
Conditions
Keywords
glaucoma, trabeculectomy, astigmatism, intraocular pressure
Brief summary
The aim of this project: 1. Confirming the modification in corneal astigmatism after trabeculectomy with MMC and intracameral administration of bevacizumab. 2. Medium-term follow up (6 months) of the induced corneal astigmatism. 3. Investigating correlations between postoperative astigmatism, particularly with the postoperative IOP.
Interventions
PROCEDUREtrabeculectomy
Filtering surgery to reduce the intra-ocular pressure.
Sponsors
Universitaire Ziekenhuizen KU Leuven
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Primary open angle glaucoma * Normal tension glaucoma * Pseudoexfoliation glaucoma * Pigment dispersion glaucoma
Exclusion criteria
* Patients who refuse to sign the informed consent. * Patients with primary angle closure glaucoma (PACG). * Patients younger than 18 years old. * Other ocular diseases besides glaucoma. * Significant corneal opacities. * Refractive error more than + or -6.00 diopters. * Visual acuity less than 0.05 * Previous intra-ocular surgery (except cataract surgery more than six months preceding the trabeculectomy). * Laser treatment for glaucoma within 6 months of the surgery.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in ocular cylinder and axis untill 6 months after trabeculectomy. | pre-operative until 6 months post-operative | Comparing the change in corneal cylinder, axis and IOP before the operation and 1,3 and 6 months after the operation. We will compare these vectors by vector analyses. |
Countries
Belgium
Outcome results
None listed