Dementia
Conditions
Keywords
Musical Dual Task Training, dementia, attention control, dual task cost, gait stability
Brief summary
The purpose of this project is to determine if the Musical Dual Task Training program improves attention control that influences measures of gait performances under dual tasking, balance, fear of falling, and behavioral disturbance in patients with mild to moderate dementia. This Musical Dual Task Training protocol is structured with musical content and patients are required to do musical tasks including singing and playing instruments contingent on visual or auditory cues while walking. This paradigm is designed to include music making because it involves great demands on attention and memory that might elicit experience-dependent plasticity in the brain. Musical Dual Task Training is proposed to strengthen brain networking for attention control that consequently may improve the gait performances in patients with dementia, as indicated by reducing dual task cost on gait.
Interventions
BEHAVIORALMusical Dual Task Training
BEHAVIORALWalking and Talking
Sponsors
Chang Gung Memorial Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
55 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* a mild to moderate dementia diagnosis with Clinical Dementia Rating (CDR) score: .5, 1, or 2 * ability to walk 10 meters independently without the use of a walker or cane, or the assistance by another person
Exclusion criteria
* other known neurologic disorders such as stroke or Parkinson's disease * significant orthopedic, visual, and hearing impairment that hinders ambulation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change from Baseline on the Trail Making Test at 2 months | Baseline and at 2 months | Trail Making Test Part A requires the participants to draw lines to connect a set of 25 circles as fast as possible following the sequential order of numbers (1,2,3…25) while still maintaining accuracy. Trail Making Test Part B is in a same format, but participants are required to alternates between numbers and letters (1, A, 2, B, etc.). The circles in Part B include both numbers (1 - 13) and letters (A - L). Results for both Part A and Part B are reported as the number of seconds required to complete the task. Higher scores indicate greater impairment. |
Secondary
| Measure | Time frame |
|---|---|
| Change from Baseline on Walking Speed during Dual tasking at 2 Months | Baseline and at 2 months |
| Change from Baseline on the Timed Up-and-Go test at 2 Months | Baseline and 2 months |
| Change from Baseline on the 7-item Short Falls Efficacy Scale International at 2 Months | Baseline and at 2 months |
| Change from Baseline on the Cohen-Mansfield Agitation Inventory scale at 2 months | Baseline and at 2 months |
| Change from Baseline on Stride Lengths during Dual Tasking at 2 Months | Baseline and at 2 months |
Countries
Taiwan
Contacts
Primary ContactYu-Cheng Pei, MD, PhD
Backup ContactYu-Ling Chen, MA, MME
Outcome results
None listed