Pertussis
Conditions
Keywords
Pertussis antibodies, Bordetella pertussis, sero-prevalence, Healthcare professionals (HCP), Spain
Brief summary
This study aims to determine the sero-prevalence of anti-pertussis antibodies among healthcare professionals at hospital centres in Spain.
Interventions
PROCEDUREBlood sample
Samples will be tested to determine the presence of anti-pertussis antibodies.
OTHERData collection
Electronic Case Report Forms (eCRF)
Sponsors
GlaxoSmithKline
Study design
Observational model
COHORT
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Written informed consent obtained from the subject. * Subjects who the investigator believes that they can and will comply with the requirements of the protocol. * Male and female healthcare professionals aged ≥18 years from selected hospitals. * Healthcare professionals in frequent contact with patients in the hospitals. * Agreeing for collection of a blood sample for the study.
Exclusion criteria
• Medical students working as healthcare professionals.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluation of the overall sero-prevalence of Bordetella pertussis infection among subjects with respect to anti-pertussis (anti-PT) antibody levels. | Day 0 of each subject at the time of enrollment. |
| Evaluation of the overall sero-prevalence of Bordetella pertussis infection among subjects with respect to anti-PT seropositivity status. | Day 0 of each subject at the time of enrollment. |
| Evaluation of the overall sero-prevalence of Bordetella pertussis infection among subjects with respect to anti-PT seronegativity status. | Day 0 of each subject at the time of enrollment. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Description of the knowledge and beliefs about whooping cough and vaccination against pertussis among healthcare professionals. | Day 0 of each subject at the time of enrollment. | — |
| Evaluation of the sero-prevalence of B. pertussis antibodies among healthcare professionals aged ≥ 18 years. | Day 0 of each subject at the time of enrollment. | By age and gender, by type of healthcare professional, by hospital department of the healthcare professional, duration of service and time spent with patients. |
| Description of the household composition of healthcare professionals to identify the proportion of healthcare professionals potentially at a higher risk of contracting and transmitting pertussis. | Day 0 of each subject at the time of enrollment. | — |
| Evaluation of the sero-prevalence of anti-pertussis antibodies among healthcare professionals by vaccination history. | Day 0 of each subject at the time of enrollment. | — |
| Evaluation of the sero-prevalence of anti-pertussis antibodies among healthcare professionals by previous history of pertussis. | Day 0 of each subject at the time of enrollment. | — |
Countries
Spain
Outcome results
None listed