Long QT Syndrome
Conditions
Brief summary
The purpose of the study is to provide comprehensive follow-up in patients with Long QT Syndrome (LQTS) and gain additional information regarding genotype-phenotype correlation and effective management and treatment options.
Interventions
None listed
Sponsors
Pediatrix
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
No minimum to 20 Years
Healthy volunteers
No
Inclusion criteria
* Children and/or young adults diagnosed with heterogeneous repolarization disorder who have genotype positive Long QT, or * Newly diagnosed mutation positive patients with a confirmed test
Exclusion criteria
* Children who are phenotypically positive with no molecular testing * Children that are phenotypically positive but genotype negative
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Adverse Cardiac Events on patients with genotype positive LQT1 who have a normal EKG and absence of symptoms, but a molecular confirmation of LQT1. | Enrollment is expected to take approximately 5 years. The patients will be followed until they are no longer cared for by a pediatric cardiology facility (typically post-college) or approximately 21 years of age. |
Secondary
| Measure | Time frame |
|---|---|
| Adverse Cardiac Events on patients with both phenotype and genotype positive. | Enrollment is expected to take approximately 5 years. The patients will be followed until they are no longer cared for by a pediatric cardiology facility (typically post-college) or approximately 21 years of age. |
Countries
United States
Outcome results
None listed