Epidemiology of Human Cytomegalovirus Excretion in the Saliva of Children Attending Nursery in France

Epidemiology of Human Cytomegalovirus Excretion in the Saliva of Children Attending Nursery in France.

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01704222

Acronym

CrèchMV

Enrollment

2001

Registered

2012-10-11

Start date

2009-09-30

Completion date

2013-09-30

Last updated

2013-11-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy Volunteers

Keywords

Children, nursery, CMV, Infection

Brief summary

Direct DNA amplification, viral isolation and specific antibody measurement in saliva from children attending nursery in France Sample collection will be done by the pediatrician the nurse, or one of the authorized investigators of the study.

Detailed description

Salivary collection kit. 3 swab for DNA research, 1 for antibodies research and 1 for virus isolation by cell growth.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

3 Years to 6 Years

Healthy volunteers

Yes

Inclusion criteria

* Children older than 3 months and less than 6 years kept in nurseries retained, regardless of the duration of custody of the child in the manger concerned.

Exclusion criteria

* Refusal of parents (lack of consent) * Refusal of the child according to his ability to understand * Uninsured social security

Design outcomes

Primary

Measure	Time frame	Description
Identification of viral shedding	1 day	Saliva using small sponges, non-invasive for the viral genome, isolating virus strains and measurement of antibody IgG and IgA.

Secondary

Measure	Time frame	Description
Evaluate the distribution of different genotypes of strains of CMV	1 day	distribution by genotype strains found

Countries

France

Outcome results