Acne Scars, Wrinkles
Conditions
Brief summary
The purpose of this study is to find out if autologous (your own) fibroblast injections are effective for the treatment of acne scars and wrinkles.
Interventions
DRUGFibroblast Treatment
PROCEDUREVehicle
Sponsors
Northwestern University
Study design
Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Age 18 or over * Bilateral acne scars or have moderate to severe wrinkles * Subjects in good health * Subjects has the willingness and the ability to understand and provide informed consent for the use of their tissue and communicate with the investigator
Exclusion criteria
* Under 18 years of age * Pregnancy or lactation * recent Accutane use in the past 6 months * prone to hypertrophic and keloidal scarring * have excessively redundant skin in the treatment area or wrinkles longer than 20 cm total * have a history of autoimmune disorders, organ transplantation, cancer not in remission, active or chronic skin disease * have a history of basal-cell carcinoma * have previously received autologous fibroblast treatment * have undergone any confounding therapy in the lower two-thirds of the face within 1 year or any investigational treatment within 30 days. * have an allergy to collagen, bovine products, local anesthetics, gentamicin, or amphotericin B * subjects who are unable to understand the protocol or to give informed consent * subjects with mental illness
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change from baseline of rater's comparisons at 6 months | Basline and 6 months |
Countries
United States
Outcome results
None listed