Intraoperative Floppy Iris Syndrome in Korean Patients Taking α1-Adrenergic Receptor Antagonists

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01704014

Enrollment

150

Registered

2012-10-11

Start date

2010-01-31

Completion date

2010-03-31

Last updated

2012-10-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intraoperative Floppy Iris Syndrome

Keywords

occurrence of

Brief summary

Intraoperative floppy iris syndrome (IFIS) is a recently described condition observed during cataract surgery. It has been hypothesized that irreversible atrophy of the iris dilator muscle associated with α1-adrenergic receptor antagonists (α1-ARA) is responsible for IFIS. However the prevalence of IFIS in Korean population is not reported. The purpose of this study is to evaluate the prevalence and clinical manifestations of IFIS in relation to iris anatomical change in Korean patients taking α1-ARA.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* clinical diagnosis of cataract * korean patients

Exclusion criteria

* history of iridocyclitis, iris neovascularization, or prior iris surgery * traumatic cataracts, zonular dialysis, or cataracts associated with ocular disease (e.g., uveitis)

Design outcomes

Primary

Measure	Time frame
occurrence of intraoperative floppy iris syndrome	intraoperative

Outcome results