Contrast Enhanced EUS in the Evaluation of Pancreatic Cancer and Pancreatic Masses

Contrast Enhanced EUS Using Definity in the Evaluation of Pancreatic Cancer and Pancreatic Masses

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01703026

Enrollment

Registered

2012-10-10

Start date

2009-08-31

Completion date

2011-10-31

Last updated

2012-10-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pancreatic Cancer

Brief summary

Contrast enhanced EUS with the sonographic contrast agent DEFINITY™ has the potential to detect pancreatic cancer at an earlier stage, to improve current method of T staging and assessment of surgical resectability and also to distinguish between benign and malignant pancreatic masses. All these will translate into better clinical outcome, and also avoid unnecessary surgery in situations of unresectable cancers.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

21 Years to No maximum

Healthy volunteers

Inclusion criteria

* Consecutive patients over a 1-year period referred for EUS examination due to suspected pancreatic lesions will be enrolled. * Age 21 years and above. * Ability to provide informed consent

Exclusion criteria

Patients with clinical conditions that preclude the use of DEFINITY™ will be excluded. These conditions are: * Right-to-left, bi-directional, or transient right-to-left cardiac shunts; * Worsening or clinically unstable congestive heart failure; * Acute myocardial infarction or acute coronary syndromes; * Serious ventricular arrhythmias or high risk for arrhythmias due to prolongation of the QT interval; * Respiratory failure; * Severe emphysema, pulmonary emboli or other conditions that cause pulmonary hypertension due to compromised pulmonary arterial vasculature; * Hypersensitivity to DEFINITY™ or its components.

Countries

Singapore

Outcome results