Stroke
Conditions
Keywords
TDCS, STROKE, APHASIA, NAMING
Brief summary
The purpose of this study is to determine the safety of transcranial direct current stimulation in aphasia therapy in acute and post-acute stroke.
Detailed description
TDCS has been shown to have a positive effect on clinical outcome in both motor rehabilitation and aphasia treatment in chronic aphasic patients. In healthy subjects the method sped up reaction times in naming and language learning tasks. In TDCS a weak current is applied to the subjects head increasing excitatory activity which might lead to improved brain function.
Interventions
DEVICEDKI ED2011
DEVICESham-TDCS
Sponsors
German Federal Ministry of Education and Research
Brandenburg Klinik, Bernau, Germany
University of Potsdam
Charite University, Berlin, Germany
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 85 Years
Healthy volunteers
No
Inclusion criteria
* first media stroke * language impairment * informed consent * right handedness * NIHSS \< 20
Exclusion criteria
* previous Epilepsy oder epileptogenic events * epilepsy typical elements in EEG * hypersensitive skin (head) * metal implants (head) * pace maker or other electronic implants * previous head/brain surgery * medication reducing seizure threshold * previous psychiatric events
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| skin irritation | 2 months |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Improved language | 2 months | improved picture naming |
Countries
Germany
Contacts
Primary ContactGerhard J Jungehuelsing, MD
Backup ContactIsabell Wartenburger, Prof. MD
Outcome results
None listed