Maternal Uterine Artery Doppler Study

A Simple Technique to Modify Maternal Uterine Artery Perfusion.

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01698957

Enrollment

Registered

2012-10-03

Start date

2012-09-30

Completion date

2016-09-30

Last updated

2016-11-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Maternal-Fetal Exchange

Keywords

Pregnant women, Uterine Artery Doppler Velocimetry

Brief summary

The purpose of this study is to detect if adding resistance to maternal blood flow from the arm will help increase the blood flow through the uterine arteries to the placenta and the baby.

Detailed description

In the setting of uteroplacental insufficiency, there is little that can be done to increase blood flow through the uterus and placenta. Historically, women with growth restricted fetuses or oligohydramnios have been placed on bed rest. Unfortunately, this treatment modality has met with only limited success. Cardiologists have long recognized the simple act of making a fist or otherwise occluding blood flow through a limb dramatically increases a person's peripheral vascular resistance. If maternal peripheral resistance can be increased, perhaps the increased differential between the maternal peripheral vascular resistance and that of the uteroplacental unit will increase flow through the uterus and placenta.

Interventions

OTHERAny patient eligible for an Ultrasound greater than or equal to 18 weeks gestation without a fetal or uterine anomaly.

bilateral Uterine artery Doppler readings pre- and during blood pressure measurement

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 50 Years

Healthy volunteers

Yes

Inclusion criteria

* Pregnant women greater than or equal to 18 years old * Able to speak and read English * Have a singleton pregnancy greater than or equal to 18 weeks gestation

Exclusion criteria

* Multiple gestation * Less than 18 weeks gestation * Uterine anomalies * Fetal anomalies * Preeclampsia * Hypertension * Inability to have BP cuff on left arm

Design outcomes

Primary

Measure	Time frame	Description
Uterine Artery Doppler	at time of routine ultrasound	The purpose of this study is to detect if adding resistance to maternal blood flow from the arm will help increase the blood flow through the uterine arteries to the placenta and the baby.

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026