Diagnostic Accuracy of Serum Bilirubin in the Prediction of Perforated Appendicitis

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01698099

Enrollment

500

Registered

2012-10-02

Start date

2009-05-31

Completion date

2012-09-30

Last updated

2012-10-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Appendicitis

Brief summary

Hyperbilirubinemia is reported to be a positive predictor in diagnosing perforated appendicitis. Therefore we analysed the diagnostic accuracy of serum bilirubin in discriminating between perforated and simple/no appendicitis. Methods: All consecutive patients undergoing appendectomy for suspected appendicitis from May 2009 to August 2011 were analysed. Primary endpoint was the diagnostic accuracy of serum bilirubin levels to detect perforated appendicitis.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

16 Years to 95 Years

Healthy volunteers

Inclusion criteria

* all patients undergoing appendectomy for suspected appendicitis

Exclusion criteria

* preexisting liver disease

Design outcomes

Primary

Measure	Time frame	Description
Diagnostic accuracy of serum bilirubin	24h within initial presentation with clinical symptoms	assessment of the diagnostic accuracy of hyperbilirubinemia (defined as serum bilirubin above 1.1 md/dl)

Countries

Germany

Outcome results