Effects of Sea Buckthorn Oil on Mucous Membranes

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01697085

Acronym

SBMM

Enrollment

116

Registered

2012-10-02

Start date

2012-10-31

Completion date

2013-05-31

Last updated

2016-01-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mucous Membranes

Keywords

sea buckthorn, mucous membrane, dryness, metabolic syndrome, vaginal atrophy

Brief summary

Aim of this study is to investigate the effects of intake of sea buckthorn oil on mucous membranes

Interventions

DIETARY_SUPPLEMENTSea buckthorn oil

DIETARY_SUPPLEMENTPlacebo oil

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

BASIC_SCIENCE

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

FEMALE

Age

55 Years to 75 Years

Healthy volunteers

Yes

Inclusion criteria

* women experiencing vaginal dryness * 55-75 years of age * at least 12 months from menstruation

Exclusion criteria

* use of estrogen replacement therapy

Design outcomes

Primary

Measure	Time frame	Description
Change from baseline in dryness related symptoms of genital mucous membranes	Interviews at baseline, at 2 months, at 3 moths (end of intervention), and daily during the study (symptom logbooks)	Interview for symptom score at baseline and study visits and a daily symptom logbook during the intervention

Secondary

Measure	Time frame
Change from baseline in vaginal pH	At baseline, at 3 months (end of intervention)

Other

Measure	Time frame	Description
Change from baseline in vaginal health index, vaginal dryness, vaginal maturity index, symptoms of dryness in other mucous membranes, markers of inflammation, oxidative stress and metabolic disorder in the circulation	At baseline, at 3 months (end of intervention)	* Vaginal health index: index score, change from baseline * Vaginal dryness: moistening of pH test strip, change from baseline * Vaginal maturity index: change from baseline * Symptoms of dryness in other mucous membranes: daily symptom logbook during the intervention * Markers of inflammation, oxidative stress and metabolic disorders: analysis from serum/plasma, change from baseline

Countries

Finland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026