Chronic Obstructive Pulmonary Disease
Conditions
Keywords
COPD, carbon dioxide, 6-minute walking test
Brief summary
The aim of this study is to investigate the development of partial pressure of carbon dioxide during the 6-min walking test and during night in Chronic Obstructive Pulmonary Disease (COPD)-patients (GOLD stage IV). Therefore the partial pressure of carbon dioxide, oxygen saturation and the heart rate are registered by a device called Sentec during the mentioned periods. In addition a measurement of activity is realised by an activity monitor (Sensewear).
Interventions
PROCEDURE6-minute walking test
submaximum exercise test
Sponsors
Schön Klinik Berchtesgadener Land
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
30 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
* COPD IV with and without a respiratory insufficiency * maximal paCO² of 55mmHg at admission (taken at rest by blood gas analysis without LTOT)
Exclusion criteria
* paCO² \> 55mmHg * non-invasive ventilation * acute exacerbation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Increase of PaCO2 more than 5mmHg | From time of starting 6-minute walking test until the time of PaCO2-increase of more than 5mmHg assessed up to 6 minutes. |
Secondary
| Measure | Time frame |
|---|---|
| Change of PaCO2 | From the beginning of the 6-minute walking test until peak PaCO2, assessed up to 6 minutes |
Countries
Germany
Outcome results
None listed