Web-based International Multi-Center Clinical Study for Parkinson's Disease

Web-based International Multi-Center Clinical Study for Parkinson's Disease; the Evaluation of Clinical Outcome Based on the Electrode Position Estimated From the Fused Images of Preoperative MRI and Postoperative CT After Bilateral STN DBS

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01696812

Enrollment

136

Registered

2012-10-01

Start date

2014-11-30

Completion date

2020-12-31

Last updated

2015-11-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Parkinson Disease

Keywords

electrodeposition, Subthalamic Nucleus, Deep Brain Stimulation, Parkinson Disease

Brief summary

The objectives of this study are (1) to compare the clinical outcome in correlation with the electrode positions estimated by web-based image fusion of the preoperative MRI and the postoperative brain CT taken at a stable period after surgery using mutual information technique in the patients with advanced Parkinson's disease (PD) after bilateral STN DBS and (2) to examine whether the documentation of the electrode position by using mutual information technique at a stable period after unilateral or bilateral STN stimulation provides useful information for the postoperative programming.

Interventions

PROCEDUREelectrode position

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

SCREENING

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

20 Years to 70 Years

Healthy volunteers

Inclusion criteria

* Advanced Parkinson Disease patients

Exclusion criteria

* The patients who have experienced any perioperative or postoperative complications * The patients with severe cognitive impairment, ongoing psychiatric problems, an unsatisfactory general condition for evaluation, or an inability

Design outcomes

Primary

Measure	Time frame
To determine the electrode positions with the relationship of the STN from the fused images of the preoperative MRI and the postoperative CT	at 1 month after surgery

Secondary

Measure	Time frame
UPDRS, H&Y, ADL scores, LEDD	at 6 and 12 months after surgery

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026