Is There a Relationship Between Previous Exposure to General Anesthesia and the Development of Alzheimer´s Disease?

A Case-control Study of Exposure to General Anesthesia and a Diagnosis of Alzheimer´s Disease Later in Life.

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01695889

Acronym

DEMA

Enrollment

877

Registered

2012-09-28

Start date

2012-05-31

Completion date

2016-07-31

Last updated

2016-03-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alzheimer´s Disease, General Anesthesia

Brief summary

The purpose of this study is to compare exposure to general anesthesia between cases with a diagnosis of Alzheimer´s disease and controls without diagnosis, through studies of medical records. The investigators wish to explore if there is a relationship between exposure to general anesthesia and the development of Alzheimer´s disease.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* Clinical diagnosis of Alzheimer´s disease * Previous exposure to anesthesia

Exclusion criteria

* Inability to retrieve medical records

Design outcomes

Primary

Measure	Time frame
Exposure to general anesthesia	Up to 20 years in retrospect

Secondary

Measure	Time frame
Exposure to inhaled anesthetics	Up to 20 years in retrospect

Countries

Sweden

Outcome results