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Influence of Yoga in Patients With Neurocardiogenic Syncope

Neurocardiogenic Syncope and the Role That Yoga Plays in People With Autonomic Dysfunction

Status
Completed
Phases
Early Phase 1
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01695525
Acronym
SYNC - YOGA
Enrollment
8
Registered
2012-09-28
Start date
2012-06-30
Completion date
2015-03-31
Last updated
2015-06-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Syncope, Vasovagal

Keywords

Neurocardiogenic Syncope, Yoga

Brief summary

Syncope is a common problem that many clinicians may encounter in various outpatient settings. Neurocardiogenic syncope (NCS) is a benign condition characterized by a self limited episode of systemic hypotension. Patients are usually managed with education on syncope, anxiety management, and coping skills. It has been established that practice of Yoga could relieve stress and anxiety. In a different study, they also found that Yoga positively influences cardiovascular function by decreasing the heart rate and blood pressure. The main objective of Yoga is to achieve control over the autonomic nervous system and able to control functions like heart rate, blood pressure and respiratory rate. Based on the findings that Yoga relieves stress and reduces heart rate, the investigators propose to study if Yoga can decrease the frequency of NCS and also reduce the symptoms associated with these episodes.

Interventions

OTHERYoga

Includes breathing exercises, postures, and meditation. Participant practices yoga at their home a minimum of 3 times per week for 1 hour per time. Participation can last for up to 1 year.

Sponsors

Dhanunjaya Lakkireddy, MD, FACC
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
No

Inclusion criteria

* Diagnosis of recurrent Neurocardiogenic syncope * At least one episode of syncope or pre-syncopal event in the last 3 months prior to enrollment

Exclusion criteria

* Previously established diagnosis of any psychiatric illness. * Previous history of Coronary Artery Disease, myocardial infarction, congestive heart failure, carotid sinus hypersensitivity * Established diagnosis of tachy and/or brady arrhythmias, except cardioinhibiotry neurocardiogenic syncope. * History of pacemaker, ICD or CRT-D implantation. * Other conditions where Yoga should be avoided are: 1. Pregnant women 2. Subjects with untreated or uncontrolled high blood pressure 3. Subjects with past history of Pnuemothorax. 4. Subjects with severe cervical spondylitis and cervical, thoracic or lumbar disc prolapse. 5. Subjects with carotid stenosis 6. Subjects with history of psychosis (evidence of acute episodes with deep and prolonged meditation) or substance abuse. 7. Subjects with the history of epilepsy ( evidence of acute episodes with deep and prolonged meditation) 8. Subjects with glaucoma 9. Subjects with history of Total Hip Replacement.

Design outcomes

Primary

MeasureTime frameDescription
Change in frequency of recurrent syncopal spells in patients with Neurocardiogenic syncope (NCS)Baseline to 3 MonthsDifferences in the incidence of syncopal spells pre and post Yoga.

Secondary

MeasureTime frame
Change in Heart Health3 Months, 1 Year

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026