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Nervous System Infections Among Patients With Febrile Seizure

Nervous System Infections Among Patients With Febrile Seizure : Retrospective Cohort Review of Consecutive Patients Admitted in 7 Pediatric Emergency Departments in Ile-de-France Between 2007 and 2011

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT01694524
Enrollment
1200
Registered
2012-09-27
Start date
2013-06-30
Completion date
2014-03-31
Last updated
2014-05-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Encephalitis, Febrile Seizure, Meningitis, Seizure

Brief summary

Few studies dealing with the risk of infectious of nervous system and the utility of lumbar puncture and of emergent neuroimaging among patients with simple febrile seizure between 3 and 11 months age and with complex seizure has been reported. None of these studies was multicentric. Recommendations about management of these children are heterogeneous. The investigators aim to study by an observational retrospective multicentric study the rate of infectious of central nervous system among patients with a complex febrile seizure and among patients between 3 and 11 months age with simple febrile seizure.

Interventions

None listed

Sponsors

Hopital Universitaire Robert-Debre
CollaboratorOTHER
Hôpital Jean Verdier
CollaboratorOTHER
Centre Hospitalier Intercommunal Creteil
CollaboratorOTHER
Versailles Hospital
CollaboratorOTHER
Centre hospitalier Lagny Marne la vallée
CollaboratorUNKNOWN
Centre hospitalier intercommunal de Poissy
CollaboratorUNKNOWN
Hôpital Armand Trousseau
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
3 Months to 5 Years
Healthy volunteers
No

Inclusion criteria

* febrile (\>38°) * Seizure

Exclusion criteria

* previous non febrile seizure * known trauma * immunodeficiancy status * Underlying illness

Design outcomes

Primary

MeasureTime frameDescription
Bacterial meningitis7 days after emergency visitResults of lumbar puncture or meningitis history in charts
Herpes simplex virus meningitis/encephalitis7 days after emergency visitResults of lumbar puncture or meningitis history in charts

Secondary

MeasureTime frame
emergent intracranial processus7 days after emergency visit

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026