Anxiety, Depression
Conditions
Keywords
Computerized neurobehavioral intervention
Brief summary
The present study will explore the effectiveness of a computer based neurobehavioral intervention in alleviating symptoms and improving emotion regulation in individuals with PTSD. It will increase understanding of psychopathology at a neural-circuit level and aid development of new non-pharmacological treatment for PTSD. The study is managed by the Etkin Lab at Stanford University in California, but participants from the entire US are welcome to participate as the study is delivered online.
Interventions
Targeted, computerized interventions completed from the participants' own home on a computer.
Sponsors
Stanford University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* current PTSD * internet access
Exclusion criteria
* lifetime psychotic disorder, * past-year substance dependence
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| WebNeuro Computerized Cognitive and Affective Assessment Battery | Baseline and 3-month | Age and gender-normed Z scores for the following measures: Sustained attention accuracy, Sustained attention lapses, Sustained attention false alarms, Working memory capacity, Visual scanning speed, Inhibition executive control, Processing speed, Maze completion executive control accuracy, Maze completion executive control speed, Immediate verbal memory, Delayed verbal memory, Inhibitory motor control accuracy, Inhibitory motor control lapses, Facial affect identification accuracy (happy, fearful, angry, sad, and disgusted), Facial affect identification speed (happy, angry, fearful, sad, or disgusted), Facial affect identity recognition accuracy (happy, angry, sad, fearful, or disgusted), Facial affect identity recognition speed (happy, sad, angry, fearful, or disgusted), Emotional conflict reaction time slowdown, Regulation of emotional conflict reaction time slowdown |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Clinician-assessed PTSD symptoms | Baseline and 3-month | Total and symptom sub scale scores from the Clinician-Administered PTSD Scale for DSM-IV (CAPS) |
Countries
United States
Outcome results
None listed