Itching, Nasal Stuffiness, Sneezing
Conditions
Keywords
allergy, cyanobacteria, sweet water swimming
Brief summary
People swimming or surfing in lake Kineret , sometimes complain of nasal stuffiness , sneezing and itching .Typically, it happens during or immediately after contact with the lake's water . The symptoms are compatible with immediate allergic reaction. Previous reports suggested a connection between similar symptoms and contact with different cyanobacteria (living in fresh water lakes). In this study we intend to prove the mechanism of these reactions. To prove the exact allergen that causes allergic rhinitis allergists perform skin tests with different suspected allergens. Likewise, we would like to perform skin tests to different proteins extracted from cyanobacteria collected in lake Kineret.
Interventions
PROCEDURESkin test with sterile extracts of different cyanobacteria
Skin test with sterile extracts of different cyanobacteria is performed on the volar aspect of the forearm. Typically, the results are read 15 minutes after performing the test. Test is regarded as positive when wheal of more than 3mm and flare appear within this time frame. Positive test indicates the existence of specific IgE to the extract in on skin mast cells .
Sponsors
Yigal Allon Kinneret Limnological Laboratory
Meir Medical Center
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* age above 18 * exposed to Lake Keneret water by swiming or sirfing
Exclusion criteria
* age under 18 * pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reproducibility of skin test to cyanobacteria | Immediately after performing the test (15 minutes) |
Countries
Israel
Contacts
Primary ContactRonit Confino-Cohen, MD
Backup ContactArnon Goldberg, MD
Outcome results
None listed