Effect of an Early Mobilization Program on Outcomes After Major Cancer Surgery

Effect of an Early Mobilization Program After Surgery on Functional Recovery and Clinical Complications in Patients Undergoing Major Cancer Surgey : a Randomized Controlled Trial

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01693172

Enrollment

108

Registered

2012-09-26

Start date

2014-12-31

Completion date

2016-01-31

Last updated

2015-08-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neoplasm

Keywords

exercise, neoplasm

Brief summary

The aim of this study is to evaluate the effect of an early postoperative physical rehabilitation program on the functional capacity and incidence of postoperative complications in patients undergoing major elective surgery for treatment of a neoplasm

Interventions

BEHAVIORALEarly mobilization program

Early postoperative supervised aerobic exercise, resistance and flexibility training

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patients who will be submitted to major surgery for cancer treatment. * Age ≥ 18 years * Reading and signing the informed consent

Exclusion criteria

Acute myocardial infarction (within the last 30 days) * Unstable Angina * Cardiac arrhythmia uncontrolled * symptomatic severe aortic stenosis * Congestive heart failure NYHA III or IV * infarction or acute pulmonary thromboembolism * pericarditis or myocarditis * Acute Endocarditis * Acute aortic dissection * Active infection * Acute renal failure * Thyrotoxicosis * Refusal to participate in the study * Inability to ambulate independently and / or inability to exercises * Presence of bone metastasis * musculoskeletal and neurological conditions that preclude the achievement of an exercise program designed for this study

Design outcomes

Primary

Measure	Time frame
Ability to walk three meters or crossing a room without assistence	at 5 days after surgery or at hospital discharge

Secondary

Measure	Time frame	Description
fatigue	at 5 and 30 days after surgery	We will assess the level of fatigue through the Piper fatigue scale
quality of life	at 5, 30, 180 and 365 days after surgery	—
length of hospital stay	at hospital discharge	—
recurrence of cancer	at 180 days after surgery	—
hospital costs	at 180 days after surgery	—
post operatorative complications	at 30 days after surgery	Clavien classification

Countries

Brazil

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 8, 2026