Pancreatic Tumor
Conditions
Keywords
pancreatic tumor
Brief summary
Pancreatic cancer is among the most serious human neoplasia and the most difficult to treat. Most patients present at diagnosis a non resectable, locally advanced or metastatic disease, with a median survival of 12 month. The aim of this study is the identification of diagnosis biomarkers, predictive of the therapeutic response. This project investigate the use of molecular analyses applied to pancreatic tumor cells collected by microbiopsy under ultrasound-endoscopy, and blood cells.
Interventions
PROCEDUREsuspected pancreatic tumor
Realization of pancreatic surgery to obtain tumor biopsy and blood samples to realize biomarkers analyses.
Sponsors
Institut Paoli-Calmettes
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Suspicion of pancreatic adenocarcinoma * Patient \> 18 years old * Social Security affiliation * Signed informed consent
Exclusion criteria
* Patient in emergency situation * Major person being the object of a legal protective measure or unable to express its consent
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Biomarkers | within twenty four hours | Genomics, transcriptomics and proteomics analyses to determine presence or absence of biomarkers |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Histology | within twenty four hours | To determine the histologic characteristics of the pancreatic tumor |
Countries
France
Contacts
PRINCIPAL_INVESTIGATORMarine GILABERT, MD
Institut Paoli-Calmettes
Outcome results
None listed