Obstructive Sleep Apnoea
Conditions
Keywords
Obstructive Sleep, Apnoea, tongue, alteration
Brief summary
The aim of this study was to evaluate the dynamic changes of the tongue in patients with obstructive sleep apnoea hypopnea syndrome (OSAHS) during sleep and while awake by using Ultrafast Magnetic Resonance Imaging (UMRI)
Detailed description
UMRI was undertaken on the upper airway in 21 OSAHS patients and 20 normal people after being deprived of sleep for one night. A series of midline sagittal images of the upper airway were obtained. The dynamic alterations of the tongue size and the distance from the tongue to X axis (an extended line from the anterior nasal spine to posterior nasal spine) and Y axis (a perpendicular line from the center of the pituitary to the X axis) were measured.Statistical comparisons between pairs of means were performed via t-tests using Spss10 software. A probability level of p\<0.05 was considered to be statistically significant.
Interventions
DEVICEUltrafast Magnetic Resonance Imaging
MRI was performed with a 1.5 superconducting magnet (Gyroscan Intera type, Philips Co. Holland) in a posterior and anterior neck coil. The sequence used to perform the ultrafast MRI was a fast gradient- echo plus sequence. Technical parameters included: echo time, 12 msec; repetition time, 2.3 msec; flap angle, 250; matrix, 192 × 512; section thickness, 7 mm. The imaging time per slice for this sequence was 0.92 sec. A total of 120 consecutive images were obtained as a single section, with a total imaging time of 110.4 seconds. MRI scanning was carried out with the subject first asleep, then whilst awake after 20 minutes in quiet respiration. All images were inputted to the PACS workstation.
Sponsors
Wenzhou Medical University
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
MALE
Age
40 Years to 55 Years
Healthy volunteers
Yes
Inclusion criteria
1. patients who are male 2. patients were diagnosed as OSAHS 3. patients underwent a thorough history (including the Epworth somnolence questionnaire) and physical examination 4. patients did not undergo any treatment 5. each subject gave written informed consent before entering the study.
Exclusion criteria
1. patients didn't sign written informed consent 2. Any situation or condition that will interfere with adherence to study activities
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| the distance from the tongue to X axis and Y axis | one night | X axis is an extended line from the anterior nasal spine to posterior nasal spine ； Y axis is a perpendicular line from the center of the pituitary to the X axis； |
Secondary
| Measure | Time frame |
|---|---|
| the tongue size | one night |
Countries
China
Outcome results
None listed